Description

[1-(7,10-Dioxabicyclo[4.4.0]Deca-1,3,5-Trien-9-Ylmethyl)-4-Piperidyl]- (4-Methylphenyl)Methanone Hydrochloride CAS NO 76362-18-0 is a high-purity, complex organic compound supplied as its hydrochloride salt. This product is valued for its role as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapeutic research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and receptor binding studies due to its specific piperidyl and aromatic structure.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals and advanced materials requiring high structural precision.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and organometallic chemistry.

Basic Information

Item	Detail
Product Name	[1-(7,10-Dioxabicyclo[4.4.0]Deca-1,3,5-Trien-9-Ylmethyl)-4-Piperidyl]- (4-Methylphenyl)Methanone Hydrochloride
CAS No.	76362-18-0
Molecular Formula	C23H25NO3 • HCl
Molecular Weight	407.91 g/mol (Free base: 371.45 g/mol)
Synonyms	4'-Methyl-4-piperidinyl benzyl ketone derivative hydrochloride; 1-[(7,10-Dioxabicyclo[4.4.0]deca-1,3,5-trien-9-yl)methyl]-4-(4-methylbenzoyl)piperidine hydrochloride; 9-[(4-Benzoyl-1-piperidinyl)methyl]-7,10-dioxabicyclo[4.4.0]deca-1,3,5-triene hydrochloride; (4-Methylphenyl)[1-[(7,10-dioxabicyclo[4.4.0]deca-1,3,5-trien-9-yl)methyl]-4-piperidinyl]methanone hydrochloride
EINECS	Contact for details

Quality Control

Every batch of this chemical intermediate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for research-grade materials. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.