Description

[1-(7,10-Dioxabicyclo[4.4.0]Deca-1,3,5-Trien-9-Ylmethyl)-4-Piperidyl]- (4-Hydroxyphenyl)Methanone, Pyridine-3-Carboxylic Acid is a high-purity, complex organic compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular architecture, combining a benzodioxole-piperidine scaffold with a hydroxyphenyl ketone and a nicotinic acid moiety, makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This product is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in developing new generation pesticides and herbicides due to its complex heterocyclic structure.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex molecules in medicinal and combinatorial chemistry.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Academic and Industrial R&D: Fundamental material for investigative chemistry and process development in university and corporate laboratories.

Basic Information

Item	Details
Product Name	[1-(7,10-Dioxabicyclo[4.4.0]Deca-1,3,5-Trien-9-Ylmethyl)-4-Piperidyl]- (4-Hydroxyphenyl)Methanone, Pyridine-3-Carboxylic Acid
CAS No.	76335-58-5
Molecular Formula	C23H23NO6
Molecular Weight	409.44 g/mol
Synonyms	1-(7,10-Dioxabicyclo[4.4.0]deca-1,3,5-trien-9-ylmethyl)-4-piperidyl-(4-hydroxyphenyl)methanone pyridine-3-carboxylic acid; 1-[(7,10-Dioxabicyclo[4.4.0]deca-1,3,5-trien-9-yl)methyl]-4-[(4-hydroxyphenyl)carbonyl]piperidine-3-carboxylic acid; 1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-hydroxybenzoyl)piperidine-4-carboxylic acid (related structural analog); Complex piperidine-benzodioxole nicotinate derivative; CAS 76335-58-5.
EINECS	Contact for details

Quality Control

Our production of [1-(7,10-Dioxabicyclo[4.4.0]Deca-1,3,5-Trien-9-Ylmethyl)-4-Piperidyl]- (4-Hydroxyphenyl)Methanone, Pyridine-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and specific impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas (e.g., nitrogen or argon) for long-term storage to prevent oxidation and hydrolysis. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.