Description

(+)-1,2,3,4,4A,9-Hexahydro-2-Methyldibenzo[C,F]Pyrimido[1,6-A]Azepine Fumarate is a high-purity, complex heterocyclic organic compound supplied as its fumarate salt. This compound is of significant interest as a key pharmaceutical intermediate or reference standard in advanced research and development. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Research Chemical: Serves as a reference standard or starting material in medicinal chemistry and pharmacological research programs.
• Process Development: Used in the development and optimization of scalable synthetic routes for complex molecular targets.
• Analytical Standard: Employed for method development, validation, and quality control testing in analytical laboratories.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel heterocyclic chemistry.

Basic Information

Product Name	(+)-1,2,3,4,4A,9-Hexahydro-2-Methyldibenzo[C,F]Pyrimido[1,6-A]Azepine Fumarate
CAS No.	76134-84-4
Molecular Formula	C22H25N3O4
Molecular Weight	395.45 g/mol
Synonyms	(+)-Hexahydro-2-Methyldibenzopyrimidoazepine Fumarate; (6aS,13bR)-5-Methyl-5,6,6a,7,8,13b-hexahydro-4H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinoline fumarate; Fumarate salt of a dibenzopyrimidoazepine derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and other relevant tests. We support cGMP compliance for materials intended for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.