Description

5,6-Dihydro-1,1,5,9,13-Desmethylretinal is a specialized synthetic retinoid derivative, a key intermediate in the research and development of novel vitamin A analogs and visual cycle modulators. This compound is valued for its precise molecular structure, which allows scientists to study and manipulate specific biological pathways related to vision, cell differentiation, and proliferation. It is primarily utilized by pharmaceutical R&D laboratories and academic research institutions focused on ophthalmology, dermatology, and oncology.

Application

• Pharmaceutical Research Intermediate: A critical building block in the synthesis of novel retinoid-based drug candidates for treating retinal diseases and skin conditions.
• Biochemical Research: Used as a molecular probe to study the structure-activity relationships (SAR) of retinoid receptors (RARs/RXRs) and their signaling pathways.
• Visual Cycle Studies: Employed in experimental models to investigate the non-canonical visual cycle and the regeneration mechanisms of visual pigments.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical chemistry laboratories.
• Academic Synthesis Projects: Used in advanced organic chemistry and medicinal chemistry courses for the synthesis of complex, biologically active molecules.

Basic Information

Product Name	5,6-Dihydro-1,1,5,9,13-Desmethylretinal
CAS No.	76080-85-8
Molecular Formula	C19H28O
Molecular Weight	272.43 g/mol
Synonyms	5,6-Dihydro-1,1,5,9,13-Desmethylretinal; 5,6-Dihydro-1,1,5,9,13-pentanorretinal; 9-cis-5,6-Dihydro-1,1,5,9,13-pentanorretinal; Desmethylretinal derivative; Retinoid intermediate 76080-85-8; Vitamin A analog intermediate; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal (related IUPAC form)
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-1,1,5,9,13-Desmethylretinal is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Solubility	Soluble in common organic solvents (e.g., DMSO, ethanol, chloroform)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.