Description

4'-Chloro-α-Methyl-3-Biphenylacetic Acid is a high-purity biphenyl acetic acid derivative, serving as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs). This compound is essential for manufacturers in the pharmaceutical, fine chemical, and advanced material research sectors seeking reliable, high-quality raw materials for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel NSAIDs and other therapeutic agents.
• Fine Chemical Synthesis: Used in research and development for creating complex organic molecules and specialty chemicals.
• API Manufacturing: Employed in the production of Active Pharmaceutical Ingredients requiring a biphenyl acetic acid core structure.
• Chemical Research: Serves as a valuable reference standard and building block in academic and industrial R&D laboratories.
• Material Science: Potential applications in the development of advanced organic materials and liquid crystals.

Basic Information

Product Name	4'-Chloro-α-Methyl-3-Biphenylacetic Acid
CAS No.	75852-56-1
Molecular Formula	C15H13ClO2
Molecular Weight	260.71 g/mol
Synonyms	2-(4'-Chloro-3-biphenylyl)propanoic Acid; 2-(4-Chloro[1,1'-biphenyl]-3-yl)propanoic Acid; 4'-Chloro-α-methyl-1,1'-biphenyl-3-acetic Acid; 3-Biphenylacetic acid, 4'-chloro-α-methyl-; [1,1'-Biphenyl]-3-acetic acid, 4'-chloro-α-methyl-; 4'-Chloro-α-methyl-3-biphenylacetic acid; 4'-Chloro-α-methylbiphenyl-3-acetic acid
EINECS	Contact for details

Quality Control

Our 4'-Chloro-α-Methyl-3-Biphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.