Description

3-Methylbutyl n-(Heptafluorobutyryl)Leucinate is a specialized fluorinated derivative of the amino acid leucine, designed for advanced chemical synthesis and analytical applications. This compound is valued for its role as a key chiral intermediate and derivatization agent, enabling precise molecular modifications. It is primarily utilized by research institutions and industrial laboratories in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds and conducting high-sensitivity analyses.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of peptide mimetics and active pharmaceutical ingredients (APIs).
• Analytical Derivatization Agent: Used in gas chromatography (GC) and mass spectrometry (MS) to enhance the detection and separation of amino acids and related compounds.
• Agrochemical Research: Employed in the development of novel fluorinated pesticides and herbicides, leveraging its unique chemical properties.
• Peptide Chemistry: Acts as a protected leucine derivative in solid-phase and solution-phase peptide synthesis.
• Material Science: Investigated as a precursor for fluorinated surfaces and specialty polymers with specific hydrophobic characteristics.
• Biochemical Research: Utilized in metabolic studies and proteomics as a tool for labeling and tracking biomolecules.

Basic Information

Product Name	3-Methylbutyl n-(Heptafluorobutyryl)Leucinate
CAS No.	75743-21-4
Molecular Formula	C16H26F7NO3
Molecular Weight	413.37 g/mol
Synonyms	Isoamyl N-(Heptafluorobutyryl)-L-leucinate; L-Leucine, N-(2,2,3,3,4,4,4-heptafluoro-1-oxobutyl)-, 3-methylbutyl ester; Heptafluorobutyryl leucine isoamyl ester; N-Heptafluorobutyryl-L-leucine isoamyl ester; 3-Methylbutyl N-(perfluorobutyryl)leucinate; Fluorinated leucine derivative; HFB-Leu-O-isoamyl
EINECS	Contact for details

Quality Control

Our 3-Methylbutyl n-(Heptafluorobutyryl)Leucinate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment and impurity profiling, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.