Description

5-(4-Methyl-Piperazin-1-Yl)-5-Oxo-Pentanoic Acid is a high-purity pharmaceutical intermediate characterized by its piperazine and carboxylic acid functional groups. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• API Synthesis: Used in the research and production of Active Pharmaceutical Ingredients (APIs) that incorporate a modified piperazine moiety.
• Bioconjugation: The carboxylic acid group enables its use as a linker molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Research: Serves as a versatile reagent in organic synthesis and medicinal chemistry research for creating compound libraries.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.

Basic Information

Product Name	5-(4-Methyl-Piperazin-1-Yl)-5-Oxo-Pentanoic Acid
CAS No.	75727-47-8
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	5-Oxo-5-(4-methylpiperazin-1-yl)pentanoic acid; 4-Methyl-1-piperazinepentanoic acid, 5-oxo-; Pentanoic acid, 5-oxo-5-(4-methyl-1-piperazinyl)-; 5-(4-Methylpiperazin-1-yl)-5-oxopentanoic acid; 5-Oxo-5-(4-methyl-1-piperazinyl)pentanoic acid; N-(4-Methylpiperazin-1-yl)-5-oxopentanamide (tautomeric form); 75727-47-8; 5-(4-Methyl-1-piperazinyl)-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Methyl-Piperazin-1-Yl)-5-Oxo-Pentanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.