Description

1,2-Dioctanoyl-Sn-Glycerol is a synthetic, regioisomerically pure diacylglycerol (DAG) featuring octanoic (caprylic) acid esterified at the sn-1 and sn-2 positions of the glycerol backbone. This specific molecular configuration makes it a valuable biochemical tool and pharmaceutical intermediate for studying lipid metabolism, signal transduction pathways, and membrane biophysics. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers engaged in advanced lipidomics and drug delivery system formulation.

Application

• Biochemical Research: As a cell-permeable diacylglycerol analog to activate protein kinase C (PKC) isoforms in cellular signaling studies.
• Pharmaceutical Intermediates: Serving as a key synthetic building block for the production of more complex glycerolipids, prodrugs, and phospholipids.
• Lipidomics Standards: Use as a high-purity reference standard for mass spectrometry calibration and quantification in lipid analysis.
• Membrane Biophysics: A component in model membrane systems (e.g., liposomes, bilayers) to study lipid-protein interactions and membrane dynamics.
• Cosmetic & Dermatological Formulations: Potential use as a skin-compatible emollient or penetration enhancer in advanced topical delivery systems.
• Food Science Research: Investigation of DAG metabolism and its metabolic effects in nutritional studies.

Basic Information

Product Name	1,2-Dioctanoyl-Sn-Glycerol
CAS No.	75685-80-2
Molecular Formula	C19H36O5
Molecular Weight	344.49 g/mol
Synonyms	1,2-Dicapryloyl-sn-glycerol; sn-1,2-Dioctanoylglycerol; 1,2-Di-O-octanoyl-sn-glycerol; Dioctanoin; Caprylic acid 1,2-diglyceride; 1,2-Di-O-octanoylglycerol; Glycerol 1,2-dioctanoate; (2S)-1,2-Di(octanoyloxy)-3-hydroxypropane
EINECS	Contact for details

Quality Control

Our 1,2-Dioctanoyl-Sn-Glycerol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the product to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single major spot
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.