Description

Methoxypolyethylene Glycol 400 Methacrylate (CAS 75537-42-7) is a specialized methacrylate-terminated polyethylene glycol (PEG) derivative designed for advanced polymer synthesis. This compound is a crucial building block for creating hydrophilic, biocompatible, and tunable polymeric materials. It is essential for R&D scientists and production engineers in the pharmaceutical, biomedical, and specialty coatings industries seeking to modify surface properties and enhance material performance.

Application

• Biomedical Hydrogels & Drug Delivery Systems: As a key monomer for synthesizing cross-linked, water-swellable hydrogels used in controlled drug release and tissue engineering scaffolds.
• Surface Modification & Bioconjugation: For grafting hydrophilic PEG brushes onto surfaces (e.g., medical devices, sensors) to impart protein resistance (anti-fouling) and improve biocompatibility.
• Reactive Macromonomer for Copolymers: Used in the synthesis of amphiphilic block and graft copolymers for applications in dispersants, emulsifiers, and stabilizers.
• UV-Curable Resins & Coatings: Serves as a hydrophilic component in formulations for UV-curable coatings, inks, and adhesives, enhancing flexibility and moisture management.
• Contact Lens & Ophthalmic Material Manufacturing: As a monomeric ingredient to increase oxygen permeability and comfort in silicone hydrogel materials.
• Chromatography Media Functionalization: For modifying stationary phases to create hydrophilic interaction liquid chromatography (HILIC) columns.

Basic Information

Product Name	Methoxypolyethylene Glycol 400 Methacrylate
CAS No.	75537-42-7
Molecular Formula	CnH2n+2O(n/9+4) (n~9) / Typically C21H38O9
Molecular Weight	~ 434.5 g/mol (for n~9)
Synonyms	mPEG400 Methacrylate; Poly(ethylene glycol) methyl ether methacrylate (Mn 400); PEG400 Monomethacrylate; 2-Methyl-2-propenoic acid 2-[2-(2-methoxyethoxy)ethoxy]ethyl ester; Methoxy PEG 400 Methacrylate; Poly(oxy-1,2-ethanediyl), α-methoxy-ω-(2-methyl-1-oxo-2-propen-1-yl)-; MPEGMA-400; O-Methoxypolyethylene Glycol 400 Methacrylate
EINECS	Contact for details

Quality Control

Our Methoxypolyethylene Glycol 400 Methacrylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure consistent purity, functionality, and performance for sensitive applications like biomedical research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under a dry inert atmosphere (e.g., nitrogen) to prevent polymerization and hydrolysis. Keep away from heat and incompatible materials such as strong oxidizing agents and initiators.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Methoxy PEG Content (NMR)	≥ 95.0%
Acid Value	≤ 0.5 mg KOH/g
Water Content (KF)	≤ 0.2%
Inhibitor (MEHQ)	100 - 250 ppm
Average Molecular Weight (Mn, GPC)	380 - 420 g/mol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.