Description

Mpeg6-Ch2Cooh CAS NO 75427-75-7 is a specialized methoxy polyethylene glycol (mPEG) carboxylic acid derivative, serving as a critical functionalized polymer intermediate. This compound is engineered to provide a reactive carboxyl group for conjugation, enabling the modification of biomolecules, surfaces, and nanoparticles. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-purity linkers for creating PEGylated therapeutics, diagnostic agents, and functional polymers.

Application

• Pharmaceutical PEGylation: A key linker for attaching polyethylene glycol chains to peptides, proteins, and oligonucleotides to improve solubility, stability, and circulation time.
• Bioconjugation: Used to functionalize antibodies, enzymes, and other biologics with diagnostic labels or therapeutic payloads via its terminal carboxylic acid group.
• Nanoparticle Surface Modification: Employed to coat quantum dots, liposomes, and polymeric nanoparticles to enhance biocompatibility and targeting capabilities.
• Hydrogel and Biomaterial Synthesis: Acts as a cross-linking agent or functional monomer in the development of smart hydrogels and tissue engineering scaffolds.
• Chromatography Media: Utilized in the preparation of affinity chromatography resins and columns for protein purification.
• Surface Plasmon Resonance (SPR): A reagent for immobilizing biomolecules on sensor chips for interaction analysis.

Basic Information

Item	Details
Product Name	Mpeg6-Ch2Cooh
CAS No.	75427-75-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	mPEG6-CH2COOH; Methoxy-PEG6-acetic acid; α-Methoxy-ω-carboxymethyl hexaethylene glycol; 2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; PEG6 methyl ether acetic acid; mPEG(6)-Acid; Carboxymethyl-PEG6-methyl ether
EINECS	Contact for details

Quality Control

Our Mpeg6-Ch2Cooh is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and Karl Fischer titration for water content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Acid Value	Contact for details
Molecular Weight Distribution (GPC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.