Description

3H-Pyrrolizine-2-Carbonyl Chloride, 3-Oxo- (9Ci) is a high-purity, reactive organic intermediate characterized by its acid chloride functionality. This compound is of significant value in synthetic organic chemistry for the efficient construction of complex heterocyclic amides and esters. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of pyrrolizine-based drug candidates, including potential kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the pyrrolizine scaffold for enhanced activity.
• Material Science: Serves as a precursor for functional polymers and advanced organic materials requiring specific heterocyclic motifs.
• Chemical Synthesis: Employed in academic and industrial R&D labs for the preparation of custom amides and esters via its highly reactive carbonyl chloride group.
• Bioconjugation: Potential use in linker chemistry for attaching small molecules to proteins or other biomolecules in probe development.

Basic Information

Product Name	3H-Pyrrolizine-2-Carbonyl Chloride, 3-Oxo- (9Ci)
CAS No.	75413-08-0
Molecular Formula	C8H6ClNO2
Molecular Weight	183.59 g/mol
Synonyms	3-Oxo-3H-pyrrolizine-2-carbonyl chloride; 2-(Chlorocarbonyl)-3-oxo-3H-pyrrolizine; 3-Oxo-3H-pyrrolizine-2-carboxylic acid chloride; Pyrrolizine-2-carbonyl chloride, 3-oxo-; 3-Oxopyrrolizine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3H-Pyrrolizine-2-Carbonyl Chloride, 3-Oxo- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high reactivity. Each lot is fully characterized and tested for critical parameters including purity, identity, and moisture content. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.