Description

[(1(10)E,2R,4R)]-2-Methoxy-8,12-Epoxygemacra-1(10),7,11-Trien-6-One is a high-purity, stereochemically defined sesquiterpene derivative with significant potential as a key intermediate in advanced organic synthesis. Its complex gemacrane skeleton and specific epoxide functionality make it a valuable building block for research and development in fine chemical and pharmaceutical applications. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries seeking novel synthetic pathways and bioactive molecule development.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Research: Used in the development of new bioactive molecules with potential herbicidal or insecticidal properties, leveraging its complex terpenoid structure.
• Fragrance & Flavor Synthesis: Acts as a precursor for the creation of unique, high-value aroma chemicals due to its gemacrane backbone, which is found in various natural fragrances.
• Academic & Industrial R&D: Employed in methodological studies and total synthesis projects to explore new chemical reactions and catalytic processes involving epoxides and strained ring systems.
• Material Science Precursor: Investigated as a starting material for synthesizing specialized polymers or coatings with specific optical or mechanical properties derived from its rigid structure.

Basic Information

Item	Detail
Product Name	[(1(10)E,2R,4R)]-2-Methoxy-8,12-Epoxygemacra-1(10),7,11-Trien-6-One
CAS No.	75412-95-2
Molecular Formula	C16H20O3
Molecular Weight	260.33 g/mol
Synonyms	2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one; (1(10)E,2R,4R)-rel-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one; Gemacra-1(10),7,11-trien-6-one, 2-methoxy-8,12-epoxy-, (1(10)E,2R,4R)-; 75412-95-2; 2-Methoxy-8,12-epoxygemacratriene-6-one
EINECS	Contact for details

Quality Control

Our [(1(10)E,2R,4R)]-2-Methoxy-8,12-Epoxygemacra-1(10),7,11-Trien-6-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.