Description

1-(4-Hydroxybenzyl)Piperazine (CAS NO 75341-33-2) is a versatile aromatic piperazine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a phenolic hydroxyl group and a piperazine ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system, as antihistamines, or as antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its structural motif for bioactivity.
• Ligand and Catalyst Preparation: Serves as a chelating agent or backbone for creating ligands used in homogeneous catalysis and metal complexation.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers, resins, and epoxy curing agents.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and colorants, especially azo dyes and photographic chemicals.
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.

Basic Information

Product Name	1-(4-Hydroxybenzyl)Piperazine
CAS No.	75341-33-2
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	4-(Piperazin-1-ylmethyl)phenol; 1-(4-Hydroxybenzyl)piperazine; N-(4-Hydroxybenzyl)piperazine; p-Hydroxybenzylpiperazine; 4-(Piperazinomethyl)phenol; 1-(p-Hydroxybenzyl)piperazine; Phenol, 4-(1-piperazinylmethyl)-
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxybenzyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.