Description

(R)-(-)-2-Methylpiperazine CAS NO 75336-86-8 is a high-purity chiral piperazine derivative, serving as a critical chiral building block and resolving agent in asymmetric synthesis. Its value lies in enabling the production of enantiomerically pure compounds, which is essential for developing pharmaceuticals with higher efficacy and reduced side effects. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of active pharmaceutical ingredients (APIs), catalysts, and advanced materials.

Application

• As a key chiral intermediate in the synthesis of enantiomerically pure pharmaceuticals, particularly central nervous system (CNS) agents and antiviral drugs.
• Utilized as a chiral ligand or catalyst in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Employed as a resolving agent for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• Serves as a building block for the development of novel chemical entities in medicinal chemistry and drug discovery research.
• Used in the preparation of specialty polymers and advanced materials where chirality influences material properties.
• Applied in agrochemical research for the synthesis of chiral pesticides and herbicides.

Basic Information

Product Name	(R)-(-)-2-Methylpiperazine
CAS No.	75336-86-8
Molecular Formula	C5H12N2
Molecular Weight	100.16 g/mol
Synonyms	(R)-2-Methylpiperazine; (R)-(-)-2-Methylpiperazine; (2R)-2-Methylpiperazine; (R)-2-MP; D-(-)-2-Methylpiperazine; (R)-2-Methylpiperazine; (R)-Piperazine, 2-methyl-; (R)-Hexahydro-2-methylpyrazine
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Methylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to meet the stringent requirements of pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.