Description

(S)-2-Methylpiperazine Hydrochloride is a high-purity chiral piperazine derivative, a critical building block in modern asymmetric synthesis. Its enantiomeric purity makes it an indispensable intermediate for the development of targeted active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) agents, antivirals, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where the specific (S)-enantiomer provides optimal biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis (e.g., hydrogenation, alkylation).
• Fine Chemical Building Block: Employed in custom synthesis and research for creating complex molecules with defined stereocenters.
• Biochemical Research: Utilized in the study of enzyme inhibitors and receptor binding studies due to its piperazine scaffold.

Basic Information

Product Name	(S)-2-Methylpiperazine Hydrochloride
CAS No.	75336-85-5
Molecular Formula	C5H13ClN2
Molecular Weight	136.62 g/mol
Synonyms	(S)-2-Methylpiperazine HCl; (S)-2-Methylpiperazine Monohydrochloride; (2S)-2-Methylpiperazine Hydrochloride; (S)-2-Methylpiperazine Hydrochloride Salt; (S)-2-Methylpiperazine Hydrochloride; (S)-2-Methylpiperazine hydrochloride; L-2-Methylpiperazine Hydrochloride; (S)-(-)-2-Methylpiperazine Hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Methylpiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.