Description

Leukotriene C-5 CAS NO 75207-09-9 is a specialized cysteinyl leukotriene, a key lipid mediator derived from arachidonic acid metabolism. This compound is of significant value in biochemical and pharmacological research for studying inflammatory pathways and receptor interactions. It is primarily needed by research institutions and pharmaceutical companies focused on respiratory diseases, allergy mechanisms, and the development of targeted anti-inflammatory therapeutics.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of leukotriene biosynthesis, metabolism, and signaling cascades.
• Pharmacological Studies: Essential for in vitro and ex vivo assays to investigate the potency and selectivity of leukotriene receptor antagonists.
• Inflammation Modeling: Applied in cellular models to simulate and study cysteinyl leukotriene-mediated inflammatory responses.
• Drug Discovery & Development: Serves as a critical tool for high-throughput screening and validation of novel compounds targeting the CysLT1 and CysLT2 receptors.
• Academic Research: Utilized in university and institutional labs for fundamental research into asthma, allergic rhinitis, and other hypersensitivity disorders.
• Analytical Standard: Employed as a certified reference material (CRM) for the calibration and validation of analytical methods like LC-MS/MS and HPLC in bioanalysis.

Basic Information

Product Name	Leukotriene C-5
CAS No.	75207-09-9
Molecular Formula	C30H47N3O8S
Molecular Weight	609.78 g/mol
Synonyms	LTC5; Leukotriene C5; 5(S)-Hydroxy-6(R)-S-cysteinylglycyl-7,9-trans-11,14-cis-eicosatetraenoic Acid; (5S,6R)-6-[(2R)-2-[[(4S)-4-Amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]sulfanyl]-5-hydroxyicosa-7,9,11,14-tetraenoic acid; 5-Hydroxy-6-S-cysteinylglycyl-7,9,11,14-eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our Leukotriene C-5 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area designated for laboratory chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.