Description

4-(6-Acetylamino-3-Nitro-2-Pyridyl)-1-Piperazinecarboxylic Acid Ethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitro and piperazine functionalities.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme function and protein interactions in biological systems.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-(6-Acetylamino-3-Nitro-2-Pyridyl)-1-Piperazinecarboxylic Acid Ethyl Ester
CAS No.	75167-23-6
Molecular Formula	C14H19N5O5
Molecular Weight	337.33 g/mol
Synonyms	Ethyl 4-(6-acetamido-3-nitropyridin-2-yl)piperazine-1-carboxylate; 1-Piperazinecarboxylic acid, 4-(6-(acetylamino)-3-nitro-2-pyridinyl)-, ethyl ester; 4-(6-Acetylamino-3-nitro-2-pyridyl)-1-piperazinecarboxylic acid ethyl ester; 75167-23-6; 2-(4-Ethoxycarbonylpiperazin-1-yl)-3-nitro-6-acetamidopyridine; Ethyl 4-[6-(acetylamino)-3-nitro-2-pyridinyl]-1-piperazinecarboxylate
EINECS	Contact for details

Quality Control

Our 4-(6-Acetylamino-3-Nitro-2-Pyridyl)-1-Piperazinecarboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.