Description

Insulin, Asnnh2(A21)- CAS NO 75027-03-1 is a high-purity, chemically modified insulin analog designed for advanced pharmaceutical research and development. This engineered peptide is critical for studying insulin receptor binding mechanisms, metabolic pathways, and the development of next-generation diabetes therapeutics. It is an essential raw material for biopharmaceutical companies, academic research institutions, and contract research organizations (CROs) focused on endocrinology and metabolic disease.

Application

• Pharmaceutical Reference Standard: Serves as a critical benchmark for the quality control and analytical validation of insulin-based drug products and biosimilars.
• Biochemical Research: Used in in vitro and in vivo studies to investigate the structure-activity relationship (SAR) of insulin analogs and their interaction with the insulin receptor.
• Drug Discovery & Development: A key intermediate in the R&D pipeline for novel, long-acting, or rapid-acting insulin formulations and delivery systems.
• Metabolic Disease Modeling: Employed in cell-based assays and animal models to study glucose metabolism, insulin signaling pathways, and the pathophysiology of diabetes.
• Diagnostic Reagent Manufacturing: Used as a calibrated antigen in the production of immunoassays and diagnostic kits for measuring insulin levels.

Basic Information

Product Name	Insulin, Asnnh2(A21)- CAS NO 75027-03-1
CAS No.	75027-03-1
Molecular Formula	C257H383N65O77S6
Molecular Weight	5807.9 g/mol
Synonyms	Insulin (human) [A21-Asn-NH2]; Human Insulin, A21-Deamido; [Asn-NH2(A21)]-Human Insulin; Insulin, A21-Asparagine Amide; Insulin Analog (A21-Asn-NH2); Insulin, Desamido-A21; Research Insulin Analog A21; CAS 75027-03-1
EINECS	Contact for details

Quality Control

Our Insulin, Asnnh2(A21)- CAS NO 75027-03-1 is manufactured under strict quality management systems. Each batch is subjected to a comprehensive suite of analytical tests, including HPLC for purity, peptide mapping for sequence confirmation, and mass spectrometry for identity verification. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 10.0%
Biological Activity	Contact for details
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.