Description

(S)-(+)-2-Methylpiperazine is a high-purity, chiral piperazine derivative that serves as a critical building block in asymmetric synthesis. Its enantiomeric purity makes it an invaluable intermediate for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with specific stereochemical requirements. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise chirality dictates biological activity and product efficacy.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel APIs, including antiviral agents, antidepressants, and anticancer drugs.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed reactions, enabling high enantioselectivity.
• Agrochemical Research: Building block for developing enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Intermediate in the production of complex molecules for material science and specialty chemicals.
• Bioconjugation & Linker Chemistry: Utilized in the design of chemical linkers for antibody-drug conjugates (ADCs) and other biopharmaceuticals.

Basic Information

Product Name	(S)-(+)-2-Methylpiperazine
CAS No.	74897-18-8
Molecular Formula	C5H12N2
Molecular Weight	100.16 g/mol
Synonyms	(S)-2-Methylpiperazine; (S)-(+)-2-Methylpiperazine; (+)-(S)-2-Methylpiperazine; (S)-2-Methylpiperazine; (2S)-2-Methylpiperazine; (S)-2-Methylpiperazine; L-2-Methylpiperazine; (S)-1,4-Diazacyclohexane
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.