Description

3H-1,2,4-Triazol-3-One, 2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)-1-Piperazinyl]Phenyl]-2-Propyl- is a high-purity, advanced pharmaceutical intermediate belonging to a class of substituted triazolone derivatives. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where consistent quality and reliable supply are paramount. It is primarily needed by R&D laboratories and manufacturing facilities in the pharmaceutical and life sciences industries focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for the development of new therapeutic compounds.
• Biochemical Research: Used in pharmacological studies to investigate receptor binding and enzyme inhibition mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production of APIs.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	3H-1,2,4-Triazol-3-One, 2,4-Dihydro-4-[4-[4-(4-Methoxyphenyl)-1-Piperazinyl]Phenyl]-2-Propyl-
CAS No.	74852-92-9
Molecular Formula	C22H27N5O2
Molecular Weight	393.49 g/mol
Synonyms	4-[4-[4-(4-Methoxyphenyl)piperazin-1-yl]phenyl]-2-propyl-2,4-dihydro-3H-1,2,4-triazol-3-one; 2-Propyl-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one; UNII-1C1D6T6P8W; 1C1D6T6P8W; 74852-92-9; 4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-2-propyl-2,4-dihydro-1,2,4-triazol-3-one
EINECS	Contact for details

Quality Control

Our 3H-1,2,4-Triazol-3-One derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.