Description

11-Trans Leukotriene C4 is a specialized eicosanoid metabolite and a stereoisomer of the potent inflammatory mediator Leukotriene C4. This compound is of significant value as a critical reference standard and analytical tool in biochemical research. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and diagnostic manufacturers focused on inflammation, asthma, and immunology pathways.

Application

• Biochemical Research Standard: Serves as a high-purity reference material for the study of leukotriene biosynthesis, metabolism, and biological activity.
• Pharmaceutical Development: Used in the discovery and validation of drugs targeting the 5-lipoxygenase pathway for conditions like asthma, allergic rhinitis, and inflammation.
• Analytical Method Development: Essential for calibrating equipment and developing precise HPLC, LC-MS, or ELISA assays to quantify leukotriene levels in biological samples.
• Metabolic Pathway Studies: A key tool for investigating the role of specific leukotriene isomers in cellular signaling and disease mechanisms.
• Diagnostic Kit Manufacturing: Used as a calibrator or component in the production of immunoassay kits for clinical and research diagnostics.

Basic Information

Product Name	11-Trans Leukotriene C4
CAS No.	74841-69-3
Molecular Formula	C30H47N3O9S
Molecular Weight	625.78 g/mol
Synonyms	(11E)-Leukotriene C4; 11-trans-LTC4; 11-E-Leukotriene C4; 5(S)-Hydroxy-6(R)-S-glutathionyl-7,9-trans-11,14-cis-eicosatetraenoic Acid; LTC4 (11-trans isomer); 11-trans-5(S),6(R)-LTC4
EINECS	Contact for details

Quality Control

Our 11-Trans Leukotriene C4 is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, solutions should be prepared in appropriate solvents and kept at -80°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
11-trans Isomer Content	≥ 98% of total leukotriene C4
Solubility	Soluble in ethanol, methanol, DMSO; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.