Description

8-Dehydroxythienamycin is a key β-lactam antibiotic intermediate and a structural analog of the potent carbapenem class. This compound is of significant value in pharmaceutical research and development for the synthesis of novel antibacterial agents. It is primarily utilized by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of advanced antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the chemical synthesis of novel carbapenem antibiotics.
• Antibacterial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of β-lactam action.
• Fine Chemical Synthesis: Employed in the preparation of specialized chemical libraries for high-throughput screening in drug discovery programs.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in antibiotic production.
• Academic Research: Utilized in university and institutional labs for studies on antibiotic resistance and the development of new therapeutic agents.

Basic Information

Product Name	8-Dehydroxythienamycin
CAS No.	74806-75-0
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	(5R,6S)-3-[(2-Aminoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[(2-aminoethyl)thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; 8-Dehydroxy Thienamycin; Dehydroxythienamycin; Antibiotic MK0787 derivative
EINECS	Contact for details

Quality Control

Our 8-Dehydroxythienamycin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.