Description

(4R,4Ar,7As,8R)-4,4A,5,6,7,7A,8,9-Octahydro-6,6,8-Trimethyl-4,8-Epoxyazuleno[5,6-C]Furan CAS NO 74778-23-7 is a high-purity, complex sesquiterpene lactone derivative with a unique epoxyazulene fused furan structure. This compound is of significant interest for advanced research and development due to its intricate molecular architecture, which serves as a valuable scaffold for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical, agrochemical, and fine chemical industries for use as a key intermediate in the synthesis of complex natural product analogs and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the research and development of new therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the development of novel, high-value crop protection agents and pesticides, leveraging its complex terpenoid backbone.
• Fine Chemical Production: Acts as a precursor for the synthesis of specialty fragrances, flavors, and other high-performance materials requiring specific stereochemistry.
• Academic & Industrial Research: Employed as a standard or starting material in organic chemistry research, catalysis studies, and methodology development for complex molecule synthesis.
• Natural Product Analog Development: Used to create synthetic analogs of natural sesquiterpenoids for structure-activity relationship (SAR) studies and bioactivity screening.

Basic Information

Product Name	(4R,4Ar,7As,8R)-4,4A,5,6,7,7A,8,9-Octahydro-6,6,8-Trimethyl-4,8-Epoxyazuleno[5,6-C]Furan
CAS No.	74778-23-7
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	4,8-Epoxyazuleno[5,6-c]furan, 4,4a,5,6,7,7a,8,9-octahydro-6,6,8-trimethyl-, (4R,4aR,7aS,8R)-; (-)-α-Cyclocostunolide; α-Cyclocostunolide; (4R,4aR,7aS,8R)-4,4a,5,6,7,7a,8,9-Octahydro-6,6,8-trimethyl-4,8-epoxyazuleno[5,6-c]furan; Azuleno[5,6-c]furan, 4,4a,5,6,7,7a,8,9-octahydro-6,6,8-trimethyl-4,8-epoxy-, (4R,4aR,7aS,8R)-
EINECS	Contact for details

Quality Control

Every batch of (4R,4Ar,7As,8R)-4,4A,5,6,7,7A,8,9-Octahydro-6,6,8-Trimethyl-4,8-Epoxyazuleno[5,6-C]Furan is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and stereochemical integrity suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.