Description

5-(4-Hydroxybenzyl)-2,4-Thiazolidinedione is a high-purity organic compound belonging to the thiazolidinedione class, a group of molecules with significant pharmacological interest. This compound serves as a critical pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research for developing new therapeutic agents. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of novel drug candidates targeting metabolic and inflammatory pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced drug candidates, particularly those targeting PPAR (Peroxisome Proliferator-Activated Receptor) pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to develop new molecules with potential anti-diabetic, anti-inflammatory, or anti-cancer properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis and regulatory submissions.
• Biochemical Research: Employed in biochemical assays and as a tool compound to study cellular mechanisms related to insulin sensitization and glucose metabolism.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities for clinical trials.

Basic Information

Product Name	5-(4-Hydroxybenzyl)-2,4-Thiazolidinedione
CAS No.	74772-78-4
Molecular Formula	C10H9NO3S
Molecular Weight	223.25 g/mol
Synonyms	5-(4-Hydroxybenzyl)thiazolidine-2,4-dione; 5-(p-Hydroxybenzyl)-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methyl]-; 5-(4-Hydroxybenzyl)-1,3-thiazolidine-2,4-dione; 5-(p-Hydroxybenzyl)thiazolidine-2,4-dione; 74772-78-4 (CAS); 5-(4-Hydroxybenzyl)-TZD
EINECS	Contact for details

Quality Control

Our 5-(4-Hydroxybenzyl)-2,4-Thiazolidinedione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.