Description

1-[5-Amino-6-[(2S,E)-2-Carboxy-3-Ethylidene-1-Azetidinyl]-5-Deoxy-β-D-Allo-Hexodialdo-1,4-Furanosyl]-1,2,3,4-Tetrahydro-2,4-Dioxo-5-Pyrimidinecarboxylic Acid is a complex, high-purity nucleoside analog derivative of significant interest in advanced pharmaceutical research and development. Its intricate molecular structure, featuring a fused azetidine and pyrimidinecarboxylic acid moiety, makes it a critical intermediate for synthesizing novel therapeutic agents. This compound is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the discovery of new antiviral and anticancer drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and drug mechanisms of action.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for the production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	1-[5-Amino-6-[(2S,E)-2-Carboxy-3-Ethylidene-1-Azetidinyl]-5-Deoxy-β-D-Allo-Hexodialdo-1,4-Furanosyl]-1,2,3,4-Tetrahydro-2,4-Dioxo-5-Pyrimidinecarboxylic Acid
CAS No.	74418-20-5
Molecular Formula	C17H20N4O10
Molecular Weight	440.37 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 1-[5-amino-6-[(2S,3E)-2-carboxy-3-ethylidene-1-azetidinyl]-5-deoxy-β-D-allo-hexodialdo-1,4-furanosyl]-1,2,3,4-tetrahydro-2,4-dioxo-; (2S,3E)-1-(5-Amino-5-deoxy-β-D-allo-hexodialdo-1,4-furanos-6-yl)-2-carboxy-3-ethylideneazetidinium-5-yl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; Nucleoside Azetidine Derivative; CAS 74418-20-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development and cGMP-grade requirements, with specifications tailored to your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.