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1-[1-[2-Hydroxy-2-[4-Hydroxy-3-(Sulfamoylamino)Phenyl]Ethyl]-4-Piperid Yl]-2-Oxo-3H-Benzoimidazole Hydrochloride CAS NO 74406-03-4
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CAS No.:74406-03-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-[1-[2-Hydroxy-2-[4-Hydroxy-3-(Sulfamoylamino)Phenyl]Ethyl]-4-Piperid Yl]-2-Oxo-3H-Benzoimidazole Hydrochloride is a high-purity, complex organic compound with significant potential in advanced pharmaceutical research and development. This compound is valued for its intricate molecular structure, which serves as a critical building block or intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.
Application
- Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new drug candidates, particularly in central nervous system (CNS) or receptor-targeted therapies.
- Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate specific biological pathways and enzyme interactions.
- Organic Synthesis: Acts as a versatile building block for medicinal chemists to create novel benzimidazole and piperidine derivative libraries for screening.
- API Development: Employed in the process development and optimization stages for potential new Active Pharmaceutical Ingredients.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
Basic Information
| Product Name | 1-[1-[2-Hydroxy-2-[4-Hydroxy-3-(Sulfamoylamino)Phenyl]Ethyl]-4-Piperid Yl]-2-Oxo-3H-Benzoimidazole Hydrochloride |
| CAS No. | 74406-03-4 |
| Molecular Formula | C21H26N6O5S • HCl |
| Molecular Weight | 515.00 g/mol (Free base: 474.53 g/mol) |
| Synonyms | 1-[1-[2-Hydroxy-2-(4-Hydroxy-3-sulfamoylaminophenyl)ethyl]-4-piperidyl]-2-benzimidazolinone hydrochloride; Benzimidazolone derivative, hydrochloride salt; 74406-03-4; UNII-7Q2F66K3QJ; 7Q2F66K3QJ; 1-(1-{2-Hydroxy-2-[4-hydroxy-3-(sulfamoylamino)phenyl]ethyl}piperidin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one hydrochloride |
| EINECS | Contact for details |
Quality Control
Our 1-[1-[2-Hydroxy-2-[4-Hydroxy-3-(Sulfamoylamino)Phenyl]Ethyl]-4-Piperid Yl]-2-Oxo-3H-Benzoimidazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development under various quality frameworks, including cGMP, as required by our clients.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
| Related Substances (HPLC) | Total impurities ≤ 2.0%; Any single impurity ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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