Description

(3R)-3Aα,4,4Aα,7,7Aα,8,9,9Aα-Octahydro-3α,5-Dimethyl-8-Methyleneazuleno[6,5-B]Furan-2(3H)-One is a high-purity, complex sesquiterpene lactone derivative with the CAS number 74320-17-5. This compound serves as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical scaffolds. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to explore new molecular entities with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and anticancer research.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex sesquiterpenoids and related natural products for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a precursor in developing new active ingredients for crop protection with novel modes of action.
• Chemical Biology Probe: Utilized as a molecular scaffold to create probes for studying biological pathways and protein interactions.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals used in flavors, fragrances, and advanced materials.
• Academic & Contract Research: Critical reagent for universities and CROs (Contract Research Organizations) engaged in advanced organic and medicinal chemistry projects.

Basic Information

Product Name	(3R)-3Aα,4,4Aα,7,7Aα,8,9,9Aα-Octahydro-3α,5-Dimethyl-8-Methyleneazuleno[6,5-B]Furan-2(3H)-One
CAS No.	74320-17-5
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	8-Methyleneazuleno[6,5-b]furan-2(3H)-one, 3a,4,4a,7,7a,8,9,9a-octahydro-3,5-dimethyl-, (3R,3aR,4aS,7aS,9aR)-; (3R,3aR,4aS,7aS,9aR)-3,5-Dimethyl-3a,4,4a,7,7a,8,9,9a-octahydro-8-methyleneazuleno[6,5-b]furan-2(3H)-one; A sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Our (3R)-3Aα,4,4Aα,7,7Aα,8,9,9Aα-Octahydro-3α,5-Dimethyl-8-Methyleneazuleno[6,5-B]Furan-2(3H)-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.