Description

Triptophenolide CAS NO 74285-86-2 is a specialized diterpenoid lactone compound of significant interest in advanced pharmaceutical research and development. Its unique tricyclic structure makes it a valuable intermediate for synthesizing novel bioactive molecules and a reference standard for analytical studies. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, well-characterized building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of new therapeutic agents, particularly in anti-inflammatory and anticancer research.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development, validation, and compound identification via HPLC, LC-MS, or NMR.
• Biochemical Research: Employed in pharmacological studies to investigate biological pathways, enzyme interactions, and structure-activity relationships (SAR).
• Natural Product Synthesis: A crucial building block in the semi-synthesis or total synthesis of complex natural products and their analogs.
• Academic & Institutional R&D: Utilized by universities and research institutes for exploratory chemistry and the discovery of new chemical entities.

Basic Information

Product Name	Triptophenolide
CAS No.	74285-86-2
Molecular Formula	C20H24O4
Molecular Weight	328.40 g/mol
Synonyms	Triptophenolide; (4bS,8aR,9R)-9-Hydroxy-4b,8,8-trimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-3-one; 3H-Phenanthro[4,5-bcd]furan-2(4bH)-one, 4b,5,6,7,8,8a,9,10-octahydro-9-hydroxy-4b,8,8-trimethyl-2-(1-methylethyl)-, (4bS,8aR,9R)-; Triptophenolid; A related diterpenoid from Tripterygium wilfordii.
EINECS	Contact for details

Quality Control

Our Triptophenolide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and commercial applications by providing material that meets stringent in-house specifications, with the capability to align with client-specific requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.