Description

Ergometrine is a potent ergot alkaloid and a key pharmaceutical active ingredient used primarily in obstetrics and gynecology. Its primary value lies in its powerful uterotonic properties, making it critical for the management of postpartum hemorrhage and other uterine atony conditions. This high-purity compound is essential for manufacturers in the global pharmaceutical industry, particularly those producing injectable solutions and other formulations for maternal healthcare. Rigorous quality control ensures its suitability for the synthesis of life-saving medications.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of injectable drugs for the prevention and treatment of postpartum hemorrhage.
• Obstetrical & Gynecological Medications: Key component in drugs used to induce uterine contractions and control bleeding after childbirth.
• Research & Development: Used in biochemical and pharmacological studies related to serotonin receptors and smooth muscle contraction.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Formulation Development: Utilized in the development of new drug delivery systems and combination therapies for uterine stimulants.

Basic Information

Product Name	Ergometrine
CAS No.	74283-21-9
Molecular Formula	C19H23N3O2
Molecular Weight	325.41 g/mol
Synonyms	Ergonovine; Ergobasine; (+)-Ergometrine; d-Ergometrine; d-Lysergic acid 1-hydroxyethylamide; 9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8β-carboxamide; (8β)-9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide
EINECS	Contact for details

Quality Control

Our Ergometrine is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality assurance protocols include identity confirmation, purity verification, and impurity profiling using advanced analytical techniques. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing all critical parameters to ensure compliance with relevant pharmacopoeial guidelines (e.g., USP, EP) and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Specific Rotation	+40° to +44° (c = 1 in pyridine)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.