Description

Di-β-Lysyl Capreomycin Iia is a semi-synthetic derivative of the tuberactinomycin antibiotic capreomycin, representing a significant advancement in the chemical modification of peptide antibiotics. This compound is valued for its potential to enhance antibacterial activity and modulate pharmacological properties, offering researchers a critical tool for developing next-generation anti-tuberculosis agents. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and fine chemical manufacturers focused on novel antibiotic synthesis and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and development of novel anti-mycobacterial agents, particularly for drug-resistant tuberculosis.
• Structure-Activity Relationship (SAR) Studies: Used to investigate the impact of lysyl modification on the potency, spectrum, and pharmacokinetics of capreomycin-class antibiotics.
• Biochemical Research: Employed as a specialized reagent to study bacterial protein synthesis inhibition and the mechanisms of action of tuberactinomycins.
• Fine Chemical Synthesis: Acts as a high-value building block for the custom synthesis of complex peptide-based antibiotic derivatives for preclinical evaluation.
• Analytical Reference Standard: Provides a characterized compound for use as a standard in HPLC, LC-MS, or NMR methods for quality control and metabolic studies.

Basic Information

Product Name	Di-β-Lysyl Capreomycin Iia
CAS No.	74240-43-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Capreomycin Iia, Di-β-Lysyl Derivative; N²,N⁶-Bis(4-aminobutyl)-Capreomycin Iia; β-Lysyl-Capreomycin Derivative; (S)-2,6-Diaminohexanoyl-Capreomycin Iia Derivative; Antibiotic LL-AB664 Derivative; Tuberactinomycin B Derivative; Peptide Antibiotic Intermediate
EINECS	Contact for details

Quality Control

Every batch of Di-β-Lysyl Capreomycin Iia is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards for fine chemicals and research materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.