Description

(N)1-Acetylisoniazid CAS NO 1078-38-2 is a key chemical intermediate and derivative of the first-line anti-tuberculosis drug, Isoniazid. This compound is valued for its role in pharmaceutical research and development, particularly in the synthesis of novel drug candidates and prodrugs. It is primarily sought by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in medicinal chemistry and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel anti-tubercular agents and other pharmacologically active molecules.
• Medicinal Chemistry Research: Used as a reference standard and starting material in drug discovery programs targeting mycobacterial infections.
• Prodrug Development: Investigated for the development of prodrug forms of Isoniazid to potentially improve pharmacokinetic properties.
• Biochemical Research: Employed in studies to understand the metabolism and mechanism of action of Isoniazid and its derivatives.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.
• Reference Standard: Supplied as a high-purity compound for analytical testing, quality control, and regulatory compliance in API manufacturing.

Basic Information

Product Name	(N)1-Acetylisoniazid
CAS No.	1078-38-2
Molecular Formula	C8H9N3O2
Molecular Weight	179.18 g/mol
Synonyms	1-Acetyl-2-isonicotinoylhydrazine; N'-Acetylisoniazid; N-Acetyl Isoniazid; 1-Acetylisonicotinoylhydrazine; Isonicotinic Acid Acetylhydrazide; Acetyl Isoniazid; 1-Acetyl-isonicotinoylhydrazine; INH Acetate
EINECS	Contact for details

Quality Control

Our (N)1-Acetylisoniazid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.