Description

(S)-tert-Butyl (1-(4-Methylpiperidin-1-Yl)-5-(3-Nitroguanidino)-1-Oxopentan-2-Yl)Carbamate (Wxc06282) is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture with a nitroguanidino functional group. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly protease inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Peptidomimetic Development: Serves as a core scaffold for creating peptide-like molecules with enhanced stability and bioavailability.
• Bioconjugation & Probe Synthesis: The reactive nitroguanidino group allows for conjugation in the development of biochemical probes and labeled compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	(S)-tert-Butyl (1-(4-Methylpiperidin-1-Yl)-5-(3-Nitroguanidino)-1-Oxopentan-2-Yl)Carbamate (Wxc06282)
CAS No.	74171-18-9
Molecular Formula	C17H32N6O5
Molecular Weight	400.48 g/mol
Synonyms	1) (S)-tert-Butyl (1-(4-Methylpiperidin-1-yl)-5-(3-nitroguanidino)-1-oxopentan-2-yl)carbamate 2) tert-Butyl N-[(2S)-1-(4-methyl-1-piperidyl)-5-[(nitroamino)carbamimidamido]-1-oxopentan-2-yl]carbamate 3) WXC-06282 4) Wxc06282 5) BOC-Protected Nitroguanidino Peptidomimetic Intermediate 6) (S)-5-(3-Nitroguanidino)-1-(4-methylpiperidin-1-yl)-1-oxopentan-2-aminium 2-tert-butoxycarbonate 7) CAS 74171-18-9
EINECS	Contact for details

Quality Control

Every batch of (S)-tert-Butyl (1-(4-Methylpiperidin-1-Yl)-5-(3-Nitroguanidino)-1-Oxopentan-2-Yl)Carbamate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.