Description

Losmiprofen is a non-steroidal anti-inflammatory drug (NSAID) compound with significant pharmacological interest. Its primary value lies in its potential as a key intermediate or active pharmaceutical ingredient (API) for the development of novel analgesic and anti-inflammatory medications. This compound is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and companies specializing in the synthesis of advanced therapeutic agents targeting pain and inflammation management.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of proprietary NSAID drug candidates.
• Active Pharmaceutical Ingredient (API) Research: Used in preclinical and clinical research for developing new oral or topical anti-inflammatory formulations.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies investigating cyclooxygenase (COX) enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	Losmiprofen
CAS No.	74168-08-4
Molecular Formula	C15H12O3
Molecular Weight	240.26 g/mol
Synonyms	2-[4-(2-Oxocyclopentylmethyl)phenyl]propanoic Acid; Losmiprofen; UNII-9I0K8629HU; (±)-2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propanoic Acid; rac-Losmiprofen; 9I0K8629HU; α-Methyl-4-(2-oxocyclopentylmethyl)benzeneacetic Acid
EINECS	Contact for details

Quality Control

Our Losmiprofen is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, related substances, and residual solvents. For pharmaceutical development purposes, material can be supplied to meet ICH Q3A/B guidelines for impurities. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.