Description

Cilostazol CAS NO 73963-72-1 is a selective phosphodiesterase III (PDE3) inhibitor with vasodilating and antiplatelet properties. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for intermittent claudication, a symptom of peripheral arterial disease.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral tablet formulations for the treatment of intermittent claudication.
• Cardiovascular Research: Used in preclinical and clinical studies investigating vasodilation, platelet aggregation inhibition, and peripheral blood flow improvement.
• Generic Drug Manufacturing: Serves as a key component for companies producing bioequivalent versions of branded cilostazol medications.
• Reference Standard: High-purity grade suitable for use as a reference standard in analytical laboratories for quality control and method validation.
• Drug Development: Utilized in the R&D of new combination therapies or novel delivery systems for cardiovascular and thrombotic disorders.

Basic Information

Product Name	Cilostazol
CAS No.	73963-72-1
Molecular Formula	C20H27N5O2
Molecular Weight	369.46 g/mol
Synonyms	6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC-13013; Pletal; Cilostazolum; Cilostazol (USP); 3,4-Dihydro-6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our Cilostazol is manufactured under strict quality management systems. It is tested to meet or exceed relevant pharmacopeial standards, including USP and EP monographs, ensuring identity, purity, strength, and composition. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Water (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.