Description

15-Hydroxy-5,8,11,13-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a key intermediate in the biosynthesis of lipoxins and other bioactive lipid mediators. Its value lies in its role as a critical research chemical for studying inflammatory pathways, cellular signaling, and the metabolism of polyunsaturated fatty acids. This high-purity compound is essential for pharmaceutical R&D, academic research in biochemistry and pharmacology, and for manufacturers of advanced analytical standards.

Application

• Biochemical Research: Used as a reference standard and precursor in studies of arachidonic acid metabolism, lipoxin synthesis, and eicosanoid signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate in the research and development of novel anti-inflammatory and pro-resolving therapeutic agents.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method development and validation in HPLC, LC-MS, and GC-MS analyses.
• Cell Biology Studies: Applied in in vitro and in vivo models to investigate the biological effects of hydroxy-eicosatetraenoic acids (HETEs) on cellular function.
• Enzymology: Utilized as a substrate for studying the activity and kinetics of lipoxygenase and cytochrome P450 enzymes.

Basic Information

Product Name	15-Hydroxy-5,8,11,13-Eicosatetraenoic Acid
CAS No.	73945-47-8
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	15-HETE; 15(S)-HETE; 15-Hydroxyeicosatetraenoic Acid; (15S)-15-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15S-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15(S)-Hydroxy-5,8,11,13-eicosatetraenoic Acid; 15-Hydroxy-5,8,11,13-icosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 15-Hydroxy-5,8,11,13-Eicosatetraenoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with your specifications. Our quality commitment supports research requiring reliable and traceable reference materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Isomeric Purity	≥ 98.0% (15S isomer)
Solubility	Soluble in ethanol, DMSO, and ethyl acetate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.