Description

α-(1-Imidazolylmethyl)-3-Biphenylmethanol Hydrochloride is a high-purity, non-racemic chiral building block and pharmaceutical intermediate of significant commercial interest. Its unique molecular architecture, featuring both imidazole and biphenyl moieties, makes it a critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Chemical Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing complex molecules with specific stereochemistry.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and molecular recognition studies.
• Biochemical Research: Employed in academic and industrial R&D for probing biological pathways and enzyme interactions.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	α-(1-Imidazolylmethyl)-3-Biphenylmethanol Hydrochloride
CAS No.	73932-31-7
Molecular Formula	C₁₇H₁₇ClN₂O
Molecular Weight	300.78 g/mol
Synonyms	α-(1-Imidazolylmethyl)-3-biphenylmethanol hydrochloride; 1-[(1H-Imidazol-1-yl)methyl]-[1,1'-biphenyl]-3-methanol hydrochloride; (RS)-1-(1H-Imidazol-1-ylmethyl)-3-phenylbenzenemethanol hydrochloride; Biphenylmethanol, α-(1H-imidazol-1-ylmethyl)-, hydrochloride; 73932-31-7; UNII-7V8A4U5785
EINECS	Contact for details

Quality Control

Our α-(1-Imidazolylmethyl)-3-Biphenylmethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.