Description

1-[10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Yl]-3-(Pyrazin-2-Yl)Azetidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused tricyclic and azetidine-pyrazine structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting central nervous system and other disorders. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, drug-like scaffold.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and new synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biological target identification and validation.

Basic Information

Product Name	1-[10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Yl]-3-(Pyrazin-2-Yl)Azetidine
CAS No.	73855-93-3
Molecular Formula	C22H21N3
Molecular Weight	327.43 g/mol
Synonyms	3-(Pyrazin-2-yl)-1-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)azetidine; 1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-3-(pyrazin-2-yl)azetidine; 5-[3-(2-Pyrazinyl)-1-azetidinyl]-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; Azetidine, 1-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-3-(2-pyrazinyl)-; Dibenzo[a,d]cycloheptene azetidine derivative
EINECS	Contact for details

Quality Control

Our 1-[10,11-Dihydro-5H-Dibenzo[A,D]Cyclohepten-5-Yl]-3-(Pyrazin-2-Yl)Azetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.