Description

Emetine Dihydrochloride Tetrahydrate is a high-purity salt form of the alkaloid emetine, widely recognized for its potent biological activity. This compound is critical for research and development in pharmacology and biochemistry, serving as a key reference standard and active ingredient. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of analytical standards who require a reliable and well-characterized source for their work.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and calibration in analytical laboratories.
• Biochemical Research: Employed in in vitro studies to investigate its mechanism of action as a protein synthesis inhibitor and its effects on various cellular pathways.
• Antiprotozoal Agent Research: Serves as a lead compound in the development of novel therapeutics for parasitic infections, such as amebiasis.
• Antiviral and Anticancer Studies: Utilized in preclinical research to explore its potential efficacy against certain viruses and in oncology research.
• Production of Analytical Reagents: A key starting material for the preparation of diagnostic kits, assay components, and other high-purity reagents.

Basic Information

Product Name	Emetine Dihydrochloride Tetrahydrate
CAS No.	73713-75-4
Molecular Formula	C₂₉H₄₀N₂O₄ · 2HCl · 4H₂O
Molecular Weight	679.66 g/mol (as tetrahydrate)
Synonyms	Emetine Hydrochloride Hydrate; Emetine 2HCl Tetrahydrate; 2,3-Didehydroemetine Dihydrochloride Tetrahydrate; Ipecacuanha Alkaloid Emetine Dihydrochloride Hydrate; NSC 33669 (as dihydrochloride); (-)-Emetine Dihydrochloride Tetrahydrate
EINECS	Contact for details

Quality Control

Our Emetine Dihydrochloride Tetrahydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for research and reference standard use. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	9.0% - 11.0% (Theoretical for Tetrahydrate: ~10.6%)
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.