Description

Dehydroemetine is a synthetic derivative of the natural alkaloid emetine, representing a key intermediate and active pharmaceutical ingredient (API) in advanced medicinal chemistry. This compound is valued for its specific biological activity and serves as a critical building block in the research and development of therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of novel drug candidates and biochemical studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of specialized anti-amoebic and investigational therapeutic agents.
• Biochemical Research: Used as a reference standard and active compound in pharmacological studies targeting specific cellular pathways.
• Medicinal Chemistry: Serves as a scaffold for the development and structure-activity relationship (SAR) studies of new chemical entities.
• API Manufacturing: Employed as an active starting material in the controlled production of prescription drug formulations under GMP conditions.
• Academic Research: Utilized in university and institutional labs for studies in parasitology and experimental pharmacology.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control testing.

Basic Information

Product Name	Dehydroemetine
CAS No.	4914-30-1
Molecular Formula	C29H38N2O4
Molecular Weight	478.63 g/mol
Synonyms	2,3-Didehydroemetine; Dehydroemetine; NSC-336628; Ro 1-9334/11; (2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine; Isoemetine
EINECS	225-526-4

Quality Control

Our Dehydroemetine is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC and NMR. The product meets stringent specifications suitable for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.