Description

Isoemetine Hydrobromide CAS NO 21026-77-7 is a high-purity, specialized alkaloid salt derivative, primarily valued for its role as a critical intermediate in advanced pharmaceutical research and synthesis. This compound is essential for developing and scaling up production processes for therapeutic agents, particularly in the fields of anti-protozoal and anti-cancer research. It is a key material for pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers who require a reliable source of well-characterized, high-quality building blocks for complex molecule development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of emetine derivatives and related therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, particularly investigating anti-amoebic and potential anti-neoplastic activities.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex alkaloid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized as a tool compound in studies of protein synthesis inhibition and cellular mechanisms.

Basic Information

Product Name	Isoemetine Hydrobromide
CAS No.	21026-77-7
Molecular Formula	C₂₉H₄₀N₂O₄ • HBr
Molecular Weight	553.56 g/mol
Synonyms	Isoemetine HBr; 2',3',4',5'-Tetradehydro-6',7',10,11-tetramethoxyemetan-1'-ium bromide; Isoemetine bromide; DL-Isoemetine hydrobromide; Emetine isomer hydrobromide; Isoemetinium bromide
EINECS	Contact for details

Quality Control

Our Isoemetine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.