Description

1-Piperazinecarboxaldehyde,4-Thiocyanato-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique bifunctional structure, incorporating both a formyl and a thiocyanate group on a piperazine scaffold, enabling diverse chemical transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures, particularly in medicinal chemistry programs targeting new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring a functionalized piperazine core.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the thiocyanate moiety can impart specific biological activity.
• Ligand Synthesis: Acts as a starting material for creating complex chelating agents and ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.
• Polymer Modification: Utilized to introduce reactive functional groups into polymer chains for creating specialty materials with tailored properties.
• Cross-coupling Reactions: The formyl and thiocyanate groups provide handles for various palladium-catalyzed and other cross-coupling methodologies.

Basic Information

Product Name	1-Piperazinecarboxaldehyde,4-Thiocyanato-(9Ci)
CAS No.	73563-22-1
Molecular Formula	C6H9N3OS
Molecular Weight	171.22 g/mol
Synonyms	4-Thiocyanatopiperazine-1-carbaldehyde; 1-Formyl-4-thiocyanatopiperazine; 4-Thiocyanato-1-piperazinecarboxaldehyde; NSC 403914; Piperazine-1-carbaldehyde, 4-thiocyanato-; 4-Isothiocyanatopiperidine-1-carbaldehyde (tautomer); 4-Thiocyanato-piperazine-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxaldehyde,4-Thiocyanato-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for the specific grade. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.