Description

Hydrogenobyrinic Acid-A,C-Diamide is a key intermediate in the synthesis of complex corrinoid compounds, including vitamin B12 and its analogs. This high-purity intermediate is critical for ensuring the quality and consistency of downstream pharmaceutical and fine chemical products. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for the development of novel therapeutics and biochemical reagents.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of Cobalamin (Vitamin B12) and related corrinoid pharmaceuticals.
• Biochemical Research: Used as a precursor in enzymatic studies and metabolic pathway research involving corrinoid-dependent systems.
• Fine Chemical Synthesis: Serves as a specialized intermediate for creating novel macrocyclic compounds and catalysts in advanced organic synthesis.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of corrinoid synthesis pathways.
• Nutritional Supplement R&D: Utilized in the research and development of advanced vitamin B12 formulations and fortified products.

Basic Information

Product Name	Hydrogenobyrinic Acid-A,C-Diamide
CAS No.	73367-51-8
Molecular Formula	C46H64N6O13
Molecular Weight	909.04 g/mol
Synonyms	Hydrogenobyrinic acid a,c-diamide; Cobyrinic acid a,c-diamide; Hydrogenobyric acid a,c-diamide; Factor V1a; 17α,18-Didehydro-cobyrinic acid a,c-diamide; Vitamin B12 biosynthetic intermediate; Corrinoid intermediate; (SP-4-2)-[13,13'-Bis(acetyloxy)-3,8,12,17-tetramethyl-2,7,18-tris(2-oxoethyl)corrin-21-idato(2-)-κN21,κN22,κN23,κN24]cobalt
EINECS	Contact for details

Quality Control

Our Hydrogenobyrinic Acid-A,C-Diamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	Reddish-brown to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.