Description

Piperazin-1-Yl-Pyrrolidin-1-Yl-Methanone is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its bifunctional structure, which incorporates both piperazine and pyrrolidine moieties, making it a versatile scaffold for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, due to its privileged heterocyclic structure.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing diverse compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis or as a precursor for functionalized catalysts.
• Agrochemical Synthesis: An intermediate in the research and development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex heterocyclic architectures.

Basic Information

Product Name	Piperazin-1-Yl-Pyrrolidin-1-Yl-Methanone
CAS No.	73331-93-8
Molecular Formula	C9H17N3O
Molecular Weight	183.25 g/mol
Synonyms	1-(1-Pyrrolidinylcarbonyl)piperazine; 1-Piperazin-1-yl-2-pyrrolidin-1-yl-ethanone; N-(Piperazin-1-yl)pyrrolidine-1-carboxamide; Pyrrolidin-1-yl(piperazin-1-yl)methanone; 73331-93-8; Piperazine, 1-(1-oxo-2-pyrrolidin-1-ylethyl)-; AKOS005258065
EINECS	Contact for details

Quality Control

Our Piperazin-1-Yl-Pyrrolidin-1-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.