Description

2-Chloro-10-Piperazino-10,11-Dihydrodibenzo[B,F]Thiepin 5-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its unique tricyclic dibenzothiepin structure. This compound is of critical importance for research and development in the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacology domains. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Key Intermediate in Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block for the development of novel psychotropic drugs and CNS-active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic pathways and optimize drug candidates.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential new chemical entities (NCEs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Institutional Research: Utilized in university and research institute laboratories for pharmacological studies and novel compound library generation.

Basic Information

Product Name	2-Chloro-10-Piperazino-10,11-Dihydrodibenzo[B,F]Thiepin 5-Oxide
CAS No.	73225-71-5
Molecular Formula	C20H21ClN2OS
Molecular Weight	372.91 g/mol
Synonyms	2-Chloro-10-(1-piperazinyl)-10,11-dihydrodibenzo[b,f]thiepin 5-oxide; Perathiepin 5-Oxide Derivative; DBTPO Derivative; 10,11-Dihydro-2-chloro-10-(1-piperazinyl)dibenzo[b,f]thiepin 5-oxide; 2-Chloro-10-piperazinodibenzo[b,f]thiepin 5-oxide; 73225-71-5; Dibenzo[b,f]thiepin, 10,11-dihydro-2-chloro-10-(1-piperazinyl)-, 5-oxide
EINECS	Contact for details

Quality Control

Our 2-Chloro-10-Piperazino-10,11-Dihydrodibenzo[B,F]Thiepin 5-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.