Description

2,5-Piperazinedione, 1,6-Dimethyl-3-Methylene- is a specialized heterocyclic diketopiperazine derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Research: Serves as a constrained scaffold for designing and synthesizing peptidomimetics to improve metabolic stability and bioavailability.
• Organic Synthesis Building Block: Used in the construction of more complex heterocyclic systems and natural product analogs due to its reactive methylene group.
• Agrochemical Research: Potential intermediate in the development of new active ingredients with specific biological activity.
• Material Science: Exploration into novel polymers or ligands where the diketopiperazine core provides specific structural or coordination properties.
• Academic & Contract Research: Essential for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2,5-Piperazinedione, 1,6-Dimethyl-3-Methylene-
CAS No.	73198-72-8
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	1,6-Dimethyl-3-methylenepiperazine-2,5-dione; 3-Methylene-1,6-dimethyl-2,5-piperazinedione; 1,6-Dimethyl-3-methylenediketopiperazine; Diketopiperazine, 1,6-dimethyl-3-methylene-; 3-Methylenepiperazine-2,5-dione, 1,6-dimethyl-; (3E)-1,6-Dimethyl-3-methylidene-2,5-diketopiperazine
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione, 1,6-Dimethyl-3-Methylene- is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.