Description

6-Amino-5-Cyano-3-Dimethoxymethyl-1-Oxy-Pyrazine-2-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazine-based heterocyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in research and development for creating novel herbicides and fungicides with specific modes of action.
• Fine Chemical Building Block: Serves as a versatile synthon in organic chemistry for constructing complex heterocyclic frameworks in academic and industrial R&D.
• Process Chemistry Development: Employed in route scouting and optimization studies for the commercial-scale production of target molecules.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for client-specific synthesis projects.

Basic Information

Product Name	6-Amino-5-Cyano-3-Dimethoxymethyl-1-Oxy-Pyrazine-2-Carboxylic Acid tert-Butyl Ester
CAS No.	73198-26-2
Molecular Formula	C13H18N4O5
Molecular Weight	310.31 g/mol
Synonyms	tert-Butyl 6-amino-5-cyano-3-(dimethoxymethyl)-1-oxido-2-pyrazinecarboxylate; 1-Oxido-6-amino-5-cyano-3-dimethoxymethyl-pyrazine-2-carboxylic acid tert-butyl ester; 6-Amino-5-cyano-3-dimethoxymethyl-1-oxido-pyrazine-2-carboxylic acid tert-butyl ester; 2-Pyrazinecarboxylic acid, 6-amino-5-cyano-3-(dimethoxymethyl)-1-oxido-, 1,1-dimethylethyl ester; 73198-26-2; tert-Butyl 6-amino-5-cyano-3-dimethoxymethyl-1-oxy-pyrazine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Cyano-3-Dimethoxymethyl-1-Oxy-Pyrazine-2-Carboxylic Acid tert-Butyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.