Description

(5S,12S)-Dihydroxy-(6E,8E,10E,14Z)-Eicosatetraenoic Acid is a specialized eicosanoid metabolite derived from arachidonic acid. This compound is a critical bioactive lipid mediator, playing a significant role in regulating inflammatory and immune responses. It is essential for researchers and developers in the pharmaceutical and life sciences sectors, particularly those focused on inflammation, immunology, and metabolic pathway research. The product is supplied with a high level of purity to ensure reliable and reproducible results in demanding applications.

Application

• Biochemical Research: Used as a high-purity reference standard and analytical reagent in lipidomics and eicosanoid research.
• Drug Discovery & Development: Serves as a key intermediate or target molecule for developing novel anti-inflammatory and immunomodulatory therapeutics.
• Cell Signaling Studies: Employed to study the role of lipoxygenase-derived mediators in cellular communication, inflammation, and resolution pathways.
• Academic Research: A vital tool for universities and research institutes investigating the molecular mechanisms of diseases related to lipid metabolism.
• Diagnostic Development: Potential use in the development of assays and kits for detecting specific lipid mediators in biological samples.

Basic Information

Product Name	(5S,12S)-Dihydroxy-(6E,8E,10E,14Z)-Eicosatetraenoic Acid
CAS No.	73151-67-4
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	5(S),12(S)-DiHETE; (5S,12S)-DiHETE; 5,12-DiHETE; Leukotriene B4 isomer; 5,12-Dihydroxyeicosatetraenoic acid; (5S,12S)-DHETE; 5(S),12(S)-Dihydroxy-6,8,10,14-eicosatetraenoic acid
EINECS	Contact for details

Quality Control

Every batch of (5S,12S)-Dihydroxy-(6E,8E,10E,14Z)-Eicosatetraenoic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC and spectroscopic methods, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.