Description

1-(((6,11-Dihydrodibenzo(B,E)Thiepin-11-Yl)Thio)Acetyl)-4-Methylpiperazine Maleate is a high-purity, non-racemic pharmaceutical intermediate and active ingredient of significant commercial interest. This compound matters due to its critical role as a key building block in the synthesis of advanced therapeutic agents, particularly in the central nervous system (CNS) and neuropharmacology domains. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers engaged in the development and production of novel psychotropic medications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of proprietary neuroactive drugs and psychotropic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as the core structural moiety for new chemical entities (NCEs) targeting CNS disorders.
• Research & Development: Used in academic and industrial research for pharmacological studies, structure-activity relationship (SAR) analysis, and metabolite identification.
• Reference Standard: Employed as a high-purity analytical standard for quality control, method validation, and regulatory submissions.
• Process Chemistry: Utilized in route scouting, optimization, and scale-up activities for cost-effective API manufacturing.

Basic Information

Product Name	1-(((6,11-Dihydrodibenzo(B,E)Thiepin-11-Yl)Thio)Acetyl)-4-Methylpiperazine Maleate
CAS No.	73150-22-8
Molecular Formula	C24H26N2O3S2
Molecular Weight	454.60 g/mol
Synonyms	4-Methyl-1-[(6,11-dihydrodibenzo[b,e]thiepin-11-yl)thio]acetyl]piperazine maleate; Zotepine Impurity; Zotepine Maleate; Zotepine Related Compound; 11-[(4-Methyl-1-piperazinyl)acetyl]thio]-6,11-dihydrodibenzo[b,e]thiepin maleate; FR-1314; Lodopin Impurity
EINECS	Contact for details

Quality Control

Our 1-(((6,11-Dihydrodibenzo(B,E)Thiepin-11-Yl)Thio)Acetyl)-4-Methylpiperazine Maleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.