Description

n-Pyrazinylcarbonyl-L-Phenylalanine Methyl Ester is a specialized chiral building block and protected amino acid derivative. This compound is of significant value in advanced pharmaceutical research and development, particularly in the synthesis of peptide-based drugs and enzyme inhibitors. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based pharmaceuticals and protease inhibitors.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the synthesis of targeted molecular libraries for drug discovery.
• Bioconjugation: Serves as a building block for creating peptide-drug conjugates or labeled peptides for diagnostic applications.
• Chemical Biology: Employed in the synthesis of substrate analogs and activity-based probes for studying enzyme mechanisms.
• Process Chemistry: Used in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and research institutes studying peptide synthesis, asymmetric synthesis, and bioorganic chemistry.

Basic Information

Item	Details
Product Name	n-Pyrazinylcarbonyl-L-Phenylalanine Methyl Ester
CAS No.	73058-37-4
Molecular Formula	C15H15N3O3
Molecular Weight	285.30 g/mol
Synonyms	L-Phenylalanine, N-(2-pyrazinylcarbonyl)-, methyl ester; Methyl N-(pyrazine-2-carbonyl)-L-phenylalaninate; (S)-Methyl 2-(pyrazine-2-carboxamido)-3-phenylpropanoate; Pyrazine-2-carboxylic acid L-phenylalanine methyl ester amide; N-(Pyrazin-2-ylcarbonyl)-L-phenylalanine methyl ester; N-Pyrazinylcarbonyl-L-phenylalanine methyl ester; 73058-37-4
EINECS	Contact for details

Quality Control

Our n-Pyrazinylcarbonyl-L-Phenylalanine Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.