Description

Atractylenolide Iii is a high-purity sesquiterpene lactone compound, a key bioactive constituent derived from *Atractylodes macrocephala*. This compound matters for its significant pharmacological potential, particularly in modulating inflammatory pathways and cellular signaling. It is a critical standard and active ingredient for research and development in the pharmaceutical, nutraceutical, and advanced cosmetic industries, where precise biological activity is paramount.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal extracts and finished pharmaceutical products.
• Bioactive Ingredient R&D: Serves as a lead compound in preclinical research for developing new anti-inflammatory and immunomodulatory agents.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements targeting immune system support and gastrointestinal health.
• Advanced Cosmetic Actives: Utilized in skincare formulations for its potential anti-inflammatory and soothing properties.
• Academic & Clinical Research: Essential for in vitro and in vivo studies investigating mechanisms of action related to sesquiterpene lactones.
• Herbal Extract Standardization: Employed to quantify Atractylenolide III content in crude extracts, ensuring batch-to-batch consistency and potency.

Basic Information

Product Name	Atractylenolide Iii
CAS No.	73030-71-4
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	Atractylenolide III; (3R,3aR,4S,9aR)-3,4,9a-Trimethyl-2,5-dioxo-2,3,3a,4,5,9a-hexahydrobenzofuro[3,2-b]furan-4-yl acetate; Atractylenolide 3; Atractylenolide-3; Atractylenolide C; 8β-Ethoxy atractylenolide III; 4,15-Epoxy-8β-ethoxy-3,7,11,11-tetramethyltricyclo[5.3.1.01,5]undec-7-en-9-one
EINECS	Contact for details

Quality Control

Every batch of Atractylenolide Iii is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic methods, to ensure compliance with high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.